Health Condition 1: P299- Cardiovascular disorder originating in the perinatal period, unspecified
Conditions
Interventions
None listed
Sponsors
Department of Obstretics and Gynaecology
Eligibility
Inclusion criteria
Inclusion criteria: • Cohort of fetuses of high-risk pregnant women who appear for antenatal care and are admitted for delivery (vaginal or caesarean) in OBG department, KMC Manipal, will be taken as cases. • Cohort of fetuses of low -risk pregnant women who appear for antenatal care and are admitted for delivery (vaginal or caesarean) with appropriate for gestational age (AGA) fetuses in OBG department, KMC Manipal, will be taken as controls.
Exclusion criteria
Exclusion criteria: • Maternal factors-Multiple pregnancy. • Fetal factors-Preterm fetuses, Fetuses with congenital anomalies and cardiac structural abnormalities,Fetal arrhythmias.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evidence of intrapartum fetal hypoxia(yes/no) by cardiotocography monitoring. Neonatal APGAR score (in points) (Apgar 7 at 5 minutes), cord blood pH (Acidosis at birth was defined cord arterial pH â?¤7.1 or lactate â?¥6.0 mmol/L or base excess -12 mmol/L), need for resuscitation(yes/no), other neonatal compromise. Timepoint: 4 years | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Need and type of resuscitation at birth; need of NIV/IV/oxygen(yes/no) â?¢ Hypoxic-Ischemic Encephalopathy (HIE), necrotizing enterocolitis (NEC), respiratory distress syndrome (RDS), intracerebral brain hemorrhage (ICH), periventricular leukomalacia (PVLM, respiratory depression, hypoglycemia, pathological hyperbilirubinemia, sepsis, prolonged neonatal ICU stay and other adverse neonatal outcomes(yes/no). Timepoint: 4 years | — |
Countries
India
Contacts
Public ContactK Prathiksha Prabhu
Assistant Professor,Department of CVT,Manipal College of Health Professions
Outcome results
None listed