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Comparison of effects of oxygen supplementation at different flow rates versus no oxygen supplementation during flexible bronchoscopy

Comparison of effects of 6L/minute oxygen supplementation versus 2L/minute versus no oxygen supplementation during flexible bronchoscopy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/051173
Enrollment
108
Registered
2023-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J189- Pneumonia, unspecified organism Health Condition 2: J189- Pneumonia, unspecified organism

Interventions

Intervention1: 2L/minute oxygen supplementation (GROUP B): Patients will be divided into three groups A B or C by block randomization technique .Group A will be compared with group B and group C .Seda

Sponsors

Kasturba medical college Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All patients above the age of 18 years requiring flexible bronchoscopy 2.Flexible bronchoscopy done through the transnasal route

Exclusion criteria

Exclusion criteria: 1.Chronic lung disease(Obstructive or restrictive lung disease) patients with FEV1 2.Oxygen saturation (SpO2) of = 95% as measured by a pulse oximeter at baseline 3.Any requirement for supplemental oxygen in the past 4.Patients with known or suspected allergy to Midazolam or Lignocaine 5.Flexible bronchoscopy done through endotracheal or tracheostomy tube or trans-oral route 6.Patients on respiratory depressant medications 7.Haemodynamically unstable patients 8.Pregnancy and lactation 9.Patients not willing for the study

Design outcomes

Primary

MeasureTime frame
Effects of 6L/minute oxygen supplementation versus 2L/minute versus no oxygen supplementation during flexible bronchoscopy i.e 1.Mean SpO2 during flexible bronchoscopy 2.Trough SpO2 during flexible bronchoscopy Timepoint: At the end of the study—

Secondary

MeasureTime frame
1.Respiratory variables: •Significant oxygen desaturation event (SpO2 below 90 percent or more than 4 percent fall of SpO2 from baseline for more than one minute during the procedure) •Respiratory rate at various time points 2.Hemodynamic variables Heart rate,Systolic blood pressure (SBP),Diastolic blood pressure (DBP) at various time points,occurrence of any arrhythmia 3.Need for FiO2 of approximately 0.9 - 1.0 to continue the procedure 4.Termination of the procedure due to persistent desaturation in spite of switching to FiO2 of approximately 0.9 - 1.0 7 5.Duration of oxygen supplementation requirement after flexible bronchoscopy 6.Total volume of oxygen consumed during and after the procedure 7.Ease of bronchoscopy procedure Timepoint: At the end of the study—

Countries

India

Contacts

Public ContactKeerthana S

Kasturba medical college , Manipal

rahul.magazine@manipal.edu9901727204

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026