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Comparison of bone fill in periodontal bony defect using self and artificial material

Comparative Evaluation of Advanced Platelet Rich Fibrin Plus and Enamel Matrix Derivative In The Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/051129
Enrollment
30
Registered
2023-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: IN THE ADVANCED PLATELET RICH FIBRIN IN TREATMENT OF PERIODONTAL INFRABONY DEFECTS DEFECT: After administration of local anesthesia
intracrevicular incisions will be performed extending to the adjacent teeth, with additional precaution to preserve the maximum of interdental gingival tissue. Full-thickness buccal and oral extended

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Stage II or III Periodontitis. Systemically healthy patient. good level of oral hygiene with Full-Mouth Bleeding Score Mouth Plaque Index Score presence of a minimum one or more 2-, 3-, or combined 2â??3-wall intrabony defect with a defect angle of 20â??40 (±5) degrees Pocket depths >= 6mm measured with UNC 15 probe. Vertical bone loss >= 4mm seen on intraoral periapical radiograph. No history of periodontal therapy in the preceding 6months. No use of antibiotics in the preceding 6months which can interfere with bone healing. Non-smokers

Exclusion criteria

Exclusion criteria: With known systemic illness such as Diabetes mellitus, arthritis and osteoporosis. Patients on systemic medications such as corticosteroids or Calcium channel blockers or taking long-term NSAIDS or taking bisphosphonates or calcium supplements. Use of tobacco in any form and alcohol. Teeth with Grade-III mobility and/or furcation involvement. Immunocompromised individuals. Pregnant or lactating females. Tooth with hopeless prognosis. Non-vital tooth with or without periapical pathology. History of radiotherapy therapy in the preceding 1 year in head and neck region.

Design outcomes

Primary

MeasureTime frame
Change in Probing depths, Clinical attachment levels, Transgingival bone sounding, Full mouth bleeding index, and Plaque index from baseline to 3 month and 6 month postoperativeTimepoint: baseline to 3 month and 6 month postoperative

Secondary

MeasureTime frame
Radiographic analysisTimepoint: baseline to 6 month postoperative

Countries

India

Contacts

Public ContactS Mrutyunjaya

SCB Dental College

drsubash007@gmail.com9437008298

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026