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AN OBSERVATIONAL STUDY ON GENETIC ASSOCIATION BETWEEN LABOUR ANALGESIA AND ANXIETY IN PREGNANT WOMAN

A PROSPECTIVE OBSERVATIONAL STUDY ON ASSOCIATION OF CATECHOL - O - METYL TRANSFERASE (COMT) GENE WITH LABOUR ANALGESIA AND ANXIETY IN PREGNANT WOMAN - laboranalgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/03/051123
Enrollment
50
Registered
2023-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Control Intervention1: Nil: Nil

Sponsors

DR VINITHIRA SRI GV
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Primi parturients with a singleton pregnancy, term (37weeks to 41 weeks+6days) gestation, cephalic presentation in the active first stage of labor willing for epidural analgesia Age 18- 35 years Height >145 cm

Exclusion criteria

Exclusion criteria: ï?? Patients who are not consenting to the study ï?? Any contraindication to vaginal delivery ï?? Non-reassuring N.S.T. ï?? Cephalopelvic disproportion ï?? Coagulopathies ï?? Prior history of depression or anxiety ï?? Contraindications to epidural analgesia ï?? History of smoking or alcoholism

Design outcomes

Primary

MeasureTime frame
To determine the level of association between COMT gene polymorphism and labor anxiety and analgesia in pregnant women.Timepoint: Baseline, 5 minutes, 10 minutes, 20 minutes, 30 minutes, 1 hour, 2 hours,6 hours, 12 hours—

Secondary

MeasureTime frame
To analyze if any incidentally found mutation in the COMT gene leads to decreased pain sensitivity.Timepoint: 1 min, 5min, 10 minutes, 30 minutes, 1 hour—

Countries

India

Contacts

Public ContactDR VINITHIRA SRI GV

BLDE(DU),SHRI B.M. PATIL MEDICAL COLLEGE, HOSPITAL AND RESEARCH INSTITUTE

shree_kori@yahoo.com9538846839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026