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A comparative study of two different doses of magnesium sulphate pre-treatment on the onset and duration of rocuronium induced neuromuscular blockade, A randomised controlled double blinded study.

A comparative study of two different doses of magnesium sulphate pre-treatment on the onset and duration of rocuronium induced neuromuscular blockade, A randomised controlled double blinded study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/051103
Enrollment
90
Registered
2023-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: To compare two different doses of magnesium sulphate pre-treatment on the onset and duration of rocuronium induced neuromuscular blockade.: Infusion of magnesium sulphate will be st

Sponsors

Dr.Anand
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and Grade II patients Mallampatti Grade I and Grade II.

Exclusion criteria

Exclusion criteria: Refusal of consent Known or anticipated difficult airway. Emergency surgeries. Pregnant patients. Patients with a BMI of 35 or more Patients with significant hepatic, renal, metabolic, neuro-muscular disorder Those with allergy to Rocuronium.

Design outcomes

Primary

MeasureTime frame
To compare two different doses of magnesium sulphate pre-treatment on the onset of rocuronium induced neuromuscular blockadeTimepoint: It is assessed every 30 sec with TOF monitoring. Onset is noted when TOF becomes zero.

Secondary

MeasureTime frame
To compare two different doses of magnesium sulphate pre-treatment on the duration of rocuronium induced neuromuscular blockade and haemodynamic changes.Timepoint: It is monitored every 2 minutes .Duration of action is determined when TOF zero becomes TOF 1

Countries

India

Contacts

Public ContactRamya J

chettinad hospital and research institute,kelambakkam,chennai.

dranandmurugan@gmail.com7708120186

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026