To compare Ondansetron versus Dexamethasone for sensation of vomiting and occurrence of vomiting after key hole surgery for removal of gallbladder.

Comparison of Ondansetron versus Dexamethasone for postoperative nausea and vomiting in laparoscopic cholecystectomy.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/051063

Enrollment

Registered

2023-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Group O: Single dose of IV ondansetron 100mcg/kg pre induction Control Intervention1: Group D: Single dose of IV dexamethasone 100mcg/kg pre induction

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 20-60years belonging to ASA I or II scheduled for elective laparoscopic cholecystectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients not willing for study 2. Allergy to medications 3. obese 4. pregnant woman 5. On antiemetic medication 6. surgeries extending beyond 4 hours

Design outcomes

Primary

Measure	Time frame
To determine the incidence and severity of nausea and vomiting within the first twenty four hours of postoperative periodTimepoint: Immediate post-anesthesia care unit 1 hour post-op 4 hours post-op 12 hours post-op 24 hours post-op	—

Secondary

Measure	Time frame
1. Need and time of rescue antiemetic requirement 2. Postoperative analgesic consumption and pain scoresTimepoint: Number of episodes of post-operative nausea and vomiting in the first 24 hours	—

Countries

India

Contacts

Public ContactDr Priyadharshini V C Moorthy

Kasturba Medical College, Manipal

shajimanipal@yahoo.co.in9449388791

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026