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To see the relation of excretion of certain molecules in urine with a decline in renal function in chronic kidney disease.

The association of Kidney tubular Clearance of Secretory Solutes with a fall in estimated glomerular filtration rate in chronic kidney disease: KICSS study - KICSS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/03/051048
Enrollment
650
Registered
2023-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N118- Other chronic tubulo-interstitialnephritis

Interventions

Intervention1: Nil: Nil

Sponsors

Dr RMLIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients of CKD with GFR between 20ml/min to 60ml/min

Exclusion criteria

Exclusion criteria: pregnancy, cirrhosis, severe heart failure, hospitalization in the last 3 months, proteinuria >1gm

Design outcomes

Primary

MeasureTime frame
To assess the relationship of longitudinal changes in eGFR with the baseline secretion score of endogenous secretory moleculesTimepoint: Every 3 months till completion of the study—

Secondary

MeasureTime frame
Chronic kidney disease (CKD) progression (â?¥50% eGFR decline or incident kidney failure requiring dialysis or kidney transplantation), a cardiovascular disease (CVD) composite (myocardial infarction, acute coronary syndrome, stroke, acute decompensated heart failure or death from cardiovascular causes)Timepoint: Every 3 months till completion of study—

Countries

India

Contacts

Public ContactAbhilash Chandra

Dr RMLIMS, Lucknow

acn393@gmail.com8176007206

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026