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EFFICIENCY OF DRUGS LIKE FENTANYL AND CLONIDINE WHEN ADDED AS ADJUVANTS TO PREVENT REBOUND PAIN IN PATIENTS UNDERGOING ANORECTAL SURGERIES UNDER SADDLE BLOCK.

TO COMPARE THE EFFICACY OF CLONIDINE AND FENTANYL AS ADJUVANTS TO HYPERBARIC 0.5% BUPIVACAINE ON PREVENTION OF REBOUND PAIN IN ANORECTAL SURGERIES UNDER SADDLE BLOCK.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/051043
Enrollment
120
Registered
2023-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K928- Other specified diseases of the digestive system

Interventions

Intervention1: 5mg 0.5% (H) Bupivacaine with 0.3ml Normal Saline: Spinal anaesthesia will be performed at either the L3-L4 or L4-L5 interspace through a midline approach using 25G Quincke’s spinal nee

Sponsors

JSSAHER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients posted for anorectal surgeries. -Ability to understand protocol and able to provide voluntary written consent. -ASA category I and II. -BMI -Height 150-170cms.

Exclusion criteria

Exclusion criteria: -Uncontrolled psychiatric disorders. -Uncontrolled medical illnesses like uncontrolled diabetes mellitus, uncontrolled hypertension, ischemic heart disease and chronic kidney disease. -Any contraindication to clonidine i.e. bradycardia. -Any contraindication to spinal anesthesia like patient refusal, infection at lumbar puncture site, coagulopathies or patients who are on anticoagulants. -Allergic to local anaesthetics. -Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of clonidine and fentanyl as adjuvants to hyperbaric 0.5% bupivacaine on prevention of rebound pain in anorectal surgeries under saddle block.Timepoint: Starting from spinal anaesthesia till 48hours after completion of surgery.—

Secondary

MeasureTime frame
-To evaluate the post operative pain scores (NRS) for the first 48 hours after surgery after the administration of intrathecal adjuvants such as clonidine and fentanyl in patients undergoing anorectal surgery under saddle block . -To assess the time taken for first rescue analgesic. -To assess the total dose of rescue analgesic requirement for 48 hours post surgery. -To assess the incidence of side effects between the groups receiving hyperbaric bupivacaine alone and in combination with fentanyl and clonidine.Timepoint: Starting from spinal anaesthesia till 48hours after completion of surgery.—

Countries

India

Contacts

Public ContactDRMURUGESH WAL

JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH

murugeshwali@gmail.com9945433173

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026