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comparison of anaesthetic properties and side effects between hyperbaric levobupivacaine and hyperbaric bupivacaine

Comparative Study of Quality of Subarachnoid Block by Using Hyperbaric Bupivacaine and Hyperbaric Levobupivacaine in Elective Lower Abdominal Surgery under Spinal Anaesthesia - SBHBHL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/03/050969
Enrollment
62
Registered
2023-03-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Block characteristics of Hyperbaric Levobupivacaine: 2.5ml Hyperbaric Levobupivacaine+0.5 ml Fentanyl will be administered intrathecally to the participants allocated to the study arm o

Sponsors

Department of Anaesthesiology Medical College Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: I. Either sex of 18 to 55 years. II.ASA Grade I and Grade II patients

Exclusion criteria

Exclusion criteria: I.Patients refuse to consent II.Local infection over spine III.Mentally retarded patients IV.Bleeding diathesis/disorder V.Active cough or respiratory tract infection, Bronchial Asthma VI.Upper airway obstruction or stenosis VII.Patients with known allergy to local anaesthetic drugs & alpha agonists VIII.Patients on any sedatives or antipsychotics IX.Hepatic impairment (CHILD B or higher) X.Renal impairment (creatinine >2 mg/dl) XI.Pregnancy

Design outcomes

Primary

MeasureTime frame
Subarachnoid Block characteristics of Hyperbaric Levobupivacaine and Hyperbaric Bupivacaine Timepoint: Onset and height of block after delivery of drug,just before leaving OT and in postoperative period at 1 hour interval upto 24 hours

Secondary

MeasureTime frame
Adverse effects i.e. nausea vomiting shivering pruritus respiratory depression sedation bradycardia hypotension etc. All the patients will be monitored for vital parameters sensory and motor blockade level of sedation and complications if any. Pulse rate Blood pressure and SpO2 will be recorded regularly throughout the peroperative period and postoperatively.Timepoint: Till l hour

Countries

India

Contacts

Public ContactDr Piyali Haldar

Medical College Kolkata

dibahaldar@gmail.com7001854692

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026