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Relation between surgery start time and inflammatory markers in pre and post operative outcome( mobility,comfort and difficulties of patient)

EFFECTS OF SURGERY START TIME ON POSTOPERATIVE CORTISOL,INTERLEUKIN-6,PAIN CATASTROPHIZING SCALE AND SHORT TERM PATIENT REPORTED OUTCOME MEASURE IN TOTAL KNEE ARTHROPLASTY-A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050947
Enrollment
104
Registered
2023-03-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: RANDOM AFTERNOON SURGERY START TIME FOR TOTAL KNEE ARTHROPLASTY PATIENTS AND THEIR CORTISOL,IL-6,PCS AND PROMS: RANDOM AFTERNOON SURGERY START TIME FOR TOTAL KNEE ARTHROPLASTY PATIENTS

Sponsors

A.I.I.M.S Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: VARUS OSTEOARTHRITIS PATIENTS UNDERGOING TOTAL KNEE ARTHROPLASTY

Exclusion criteria

Exclusion criteria: REVISION TOTAL KNEE ARTHROPLASTY,THEUMATOID ARTHRITIS,VALGUS KNEE,INFECTIVE/SEPTIC ARTHRITIS,ACUTE CORONARY SYNDROME HISTORY,CVA , DVT, ON STEROIDS,NEUROLOGICAL/PSYCHIATRIC PATHOLOGY,PROGRESSIVE SERIOUS COMORBITIES(CANCER,HIV)

Design outcomes

Primary

MeasureTime frame
TO ESTABLISH EFFECTS OF SURGERY START TIME(8 AM VS 2PM) ON PATIENTS REPORTED OUTCOME MEASURE(PCS,KSS,VAS,EQ5D,SF12 AND OKS SCORES) AND INFLAMMATORY MARKERS SERUM LEVELS.Timepoint: PREOPERATIVE SAMPLES AND SCORES, POST OPERATIVE DAY 1,POST OPERATIVE DAY 2,POST OPERATIVE DAY 3 AND 3 MONTHS SAMPLES AND SCORES AFTER SURGERY—

Secondary

MeasureTime frame
TO LOOK FOR 90 DAY POST OPERATIVE ADVERSE EVENTS IN PATIENTS WITH RAISED PREOPERATIVE INFLAMMATORY MARKERS TO ASSESS POST OPERATIVE PATIENT SATISFACTION IN TKA AND RELATE WITH PAIN CATASTROPHIZING SCALE TO ASSESS CLINICAL,RADIOLOGICAL AND FUNCTIONAL OUTCOMETimepoint: 3 MONTHS FOLLOW UP—

Countries

India

Contacts

Public ContactDr Abhay Elhence

Dept of Orthopaedics, A.I.I.M.S. Jodhpur

dr.saurabhortho@gmail.com7023578365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026