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A clinical trial to study the effects of two drugs, Dexamethasone and Triamcinolone Acetonide on Post-Operative Pain after Root Canal Treatment of Teeth with Irreversible Pulpitis

Efficacy of Pre-operative submucosal injection of Dexamethasone And Triamcinolone Acetonide on Post-Operative Pain following endodontic treatment of teeth with Irreversible Pulpitis: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050856
Enrollment
30
Registered
2023-03-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: GROUP II- dexamethasone (8mg) GROUP III-triamcinolone acetonide (40mg): In group 2: 8 mg, 2 ml dexamethasone will be administrated after local anesthesia ,submucosally into the mucobuc

Sponsors

DR PARI ANAND
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Healthy adults aged 18-50 years of age with symptomatic irreversible pulpitis. • Patients with good general health and no chronic systemic diseases. • Patients with a radiographically normal periapical region

Exclusion criteria

Exclusion criteria: • Teeth with periapical pathology, abscess, calcified canals or aberrant anatomy. • Patients with History of allergy to Local anesthesia or any other experimental drugs. • Patients with systemic disorders, pregnant and breastfeeding mothers and any conditions that contradict use of steroids. • Patients with use of analgesics or anti-inflammatory drugs 12 hours prior to the procedure.

Design outcomes

Primary

MeasureTime frame
post operative pain using Heft-Parker visual analogue scale (HP VAS)Timepoint: PRE-OP, POST-OP AFTER 6HRS, 12HRS, 24HRS,48HRS AND 72 HRS.

Secondary

MeasureTime frame
POST OPERATIVE PAIN USING Heft-Parker visual analogue scale (HP VAS)Timepoint: PRE-OP,POST-OP AFTER 6HRS, 12HRS,24HRS,48HRS, 72 HRS

Countries

India

Contacts

Public ContactDR PARI ANAND

THE OXFORD DENTAL COLLEGE

dr.jayreddy@gmail.com8553538792

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026