Comparison of analgesic effect of ropivacaine with dexmedetomidine and ropivacaine with clonidine in lower limb orthopaedic surgeries

Efficacy of analgesic effect of dexmedetomidine versus clonidine added to intrathecal hyperbaric ropivacaine in lower limb orthopedic surgeries- a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050845

Enrollment

Registered

2023-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Spinal Anaesthesia with 0.75% Ropivacaine: Spinal Anaesthesia is the choice for lower limb Orthopaedic surgeries Control Intervention1: Adjuvant : Dexmedetomidine and clonidine: Dexmede

Eligibility

Inclusion criteria

Inclusion criteria: Patients with 18-60 years ASA I and ASA II Weight - 50-80 kgs Orthopaedic lower limb cases

Exclusion criteria

Exclusion criteria: ASA III and more Hypersensitivity to any drugs used in study Uncontrolled diabetic mellitus and hypertension Cardiac dysrhythmias Coagulopathies

Design outcomes

Primary

Measure	Time frame
To compare post-operative analgesia of dexmedetomidine versus clonidine as adjuvant added to hyperbaric ropivacaineTimepoint: To compare post-operative dexmedetomidine versus Clonidine as adjuvant added to hyperbaric ropivacaine	—

Secondary

Measure	Time frame
Motor blockade Sensory blockadeTimepoint: Motor 7 hrs Sensory 7hrs	—

Countries

India

Contacts

Public ContactE Shanmugavalli

Aarupadai veedu medical college and hospital

vallijegan@gmail.com9940882722

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026