Health Condition 1: E519- Thiamine deficiency, unspecified Health Condition 2: E519- Thiamine deficiency, unspecified
Conditions
Interventions
Intervention1: Thiamine with Vitamin C: Thiamine: Intravenous injection 2mg/kg IV as an initial bolus dose followed by 1-2 mg/kg/day,
Supplementing vitamin C 1 g
Initial duration of administration- 10
Sponsors
Manjeeta Kumari
Eligibility
Inclusion criteria
Inclusion criteria: • Adult patients (18 - 65â??years old) admitted ICU patients. • Base line SOFA Score of individual at time of admission.
Exclusion criteria
Exclusion criteria: • Patients who are taking drugs that affect vitamins absorption and metabolism. • Patients admitted to ICU for post operative monitoring or undergoing blood purifications. • Patients on regular haemodialysis or plasmapheresis or on going bleeding. • Extreme of ages i.e children 65 yrs. • Patients whose chances of survival is very less
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| primary outcome as the effect on mortality with treatment among critically ill patientsTimepoint: Outcome observed till first 10 days of treatment and further till 28 days of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| o Duration of ICU stay. o Effect on SOFA score. o Number of free days of ventilation. Timepoint: till ICU stay | — |
Countries
India
Contacts
Public ContactDr Arvind Kumar
IGIMS, Patna
Outcome results
None listed