Health Condition 1: G409- Epilepsy, unspecified
Conditions
Interventions
Intervention1: Group A will be given antiepileptic agent/agents plus probiotics
: Cases i.e. group A will be given antiepileptic along with probiotic containing not less than 1.25 billion cells Lacto
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children 1 -18 years age group 2. Those diagnosed with Epilepsy as per ILAE 2017 criteria with 3 or more self-reported seizure in last 6 months. 3. Acceptance and informed consent for inclusion of patient in study protocol.
Exclusion criteria
Exclusion criteria: 1. 2. Chronic gastrointestinal disease. 3. Hepatic and Renal insufficiency. 4. Immunocompromised. 5. Use of antibiotics, probiotics or anti-inflammatory drugs in past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in seizure frequency at 6 months follow up as compared from baseline seizure frequencyTimepoint: Baseline, 3 months and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of treatment emergent adverse events (safety and tolerability) like allergic reactions, gastrointestinal upset in the form of diarrhea, bloating, flatulence.Timepoint: 3 months and 6 months and as reported | — |
Countries
India
Contacts
Public ContactDr Harprinder Kaur
Government Medical College and Hospital Chandigarh
Outcome results
None listed