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A study to compare the effects of 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine for spinal anaesthesia in cesarean section

A Comparative study on the effects of 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine for spinal anaesthesia in cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050810
Enrollment
70
Registered
2023-03-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Comparison between 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric bupivacaine: 2.2-2.4 ml (11-12mg) of the drug with 0.2ml (0.06mg) buprenorphine in respective groups will be given

Sponsors

Dr Ashwini Buragohain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status 2 2. Normal singleton pregnancy with a gestational period of minimum 37 weeks 3. Elective cesarean section under spinal anesthesia 4. Informed and written consent. 5. Normal BMI range (18.5-24.9)

Exclusion criteria

Exclusion criteria: 1. Allergy to study drugs 2. Infection at the site of block 3. Patient with known coagulopathy or patients on anticoagulation therapy. 4. Patient with pregnancy induced hypertension or gestational diabetes mellitus 5. Patient with fetal distress 6. Patient with cardiac and renal disease 7. Any neurological deficit in lower limbs, spinal deformity, previous spinal surgery if any

Design outcomes

Primary

MeasureTime frame
To compare the duration of analgesia in each groupTimepoint: Time from injection of drug administration to the patients first request for rescue analgesia or NRS score more than 4

Secondary

MeasureTime frame
To compare the duration of analgesia in each groupTimepoint: Time from injection of drug administration to the patients first request for rescue

Countries

India

Contacts

Public ContactDr Ashwini Buragohain

Gauhati Medical College and Hospital

rajibhazarika8@gmail.com9864063140

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026