Health Condition 1: S720- Fracture of head and neck of femur Health Condition 2: S826- Fracture of lateral malleolus Health Condition 3: S724- Fracture of lower end of femur Health Condition 4: S823- Fracture of lower end of tibia Health Condition 5: S825- Fracture of medial malleolus Health Condition 6: S820- Fracture of patella Health Condition 7: S723- Fracture of shaft of femur Health Condition 8: S824- Fracture of shaft of fibula Health Condition 9: S822- Fracture of shaft of tibia Health C
Conditions
Interventions
Intervention1: Hyperbaric ropivacaine with dexmedetomidine: 2.5 ml of hyperbaric ropivacaine (0.75%) with 10 mcg of dexmedetomidine intrathecally, effects observed for 24 hrs after spinal anesthesia.
Sponsors
BPS govt medical college
Eligibility
Inclusion criteria
Inclusion criteria: (A)ASA physical status l and II patients between age group 18-65 years posted for elective lower limb surgeries. (B)Patients giving written informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: 1.Patientâ??s refusal to participate in study. 2.Any contraindication to spinal anesthesia: a.Infection at the site of injection b.Raised Intracranial Pressure c.Pre-Existing neurological deficits d.Bleeding disorders e.Severe Hypovolemia f.Patients with anatomical spinal deformity 3.History of allergy to drugs under study. 4.Patients having underlying systemic disorders (history of uncontrolled diabetes mellitus, hypertension, peptic ulcer disease, glaucoma, fungal or viral infection). 5.History of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the blockade characteristics (i.e., onset and duration of sensory blockade) after administration of spinal anesthesia with hyperbaric bupivacaine (0.5%) and hyperbaric ropivacaine (0.75%) with dexmedetomidine as an adjuvant for conduct of lower limb surgeries in both the groups. Timepoint: Patients will be assessed bilaterally for loss of cold sensation to spirit swab in the anterior axillary line at every 1-minute interval till maximum blockade achieved at T10 level for 5-10 minutes.Duration of sensory blockade will be taken as when the patient complained of pain at the surgical site i.e., need for first rescue analgesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor blockade and hemodynamic changesTimepoint: At every minute interval, motor blockade assessment will be done till maximum motor blockade achieved (Grade 3). Duration of motor blockade will be taken from the onset of motor blockade to complete motor recovery (Grade 0). Blood pressure, heart rate and oxygen saturation will be measured every 1 minutes after the administration of spinal anesthesia for first 5 minutes then every 5 minutes till the completion of surgery | — |
Countries
India
Contacts
Public ContactDr Rishika Parihar
Bhagat Phool SINGH Government Medical College FOR Wome
Outcome results
None listed