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Study to know the effect of two drugs after removing endotracheal tube.

A Comparative Study Between Efficacy Of Intracuff 2% Lignocaine Versus Dexamethasone( 8mg ) On Post Extubation Cough, Sore Throat And Hoarseness Of Voice In Patients Undergoing Elective Surgery Under Ge neral Anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050769
Enrollment
60
Registered
2023-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexamethasone: Endotracheal cuff will be filled with dexamethasone (8 mg )solution that will prevent air leak during positive pressure ventilation,we will observe intraoperatively and 2

Sponsors

DR UMESH N P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient willing to give informed consent. 2.Age between 18-65 years of either gender. 3.American Society of Anaesthesiologist (ASA) grade I and II. 4.Modified Mallampatti grade I-II 5.Patients undergoing elective surgical procedures of duration 90 to 120 minutes under general anesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing emergency surgeries. 2.Procedures requiring perioperative nasogastric tube placement. 3.Patients with a high risk of aspiration. 4.Anticipated difficult airway 5.Pregnant women. â?? Active upper respiratory tract infections. â?? Preoperative sore throat. â?? Previous history of Gastroesophageal reflux disease (GERD). â?? Head and neck surgeries and surgeries requiring prone position.

Design outcomes

Primary

MeasureTime frame
TO DETERMINE THE EFFICACY OF INTRACUFF DEXAMETHASONE (8 MG ) WHEN COMPARED TO 2% LIGNOCAINE ON POST EXTUBATION RESPONSE IN PATIENTS UNDERGOING ELECTIVE SURGERIESTimepoint: 2hrs, 6hrs, 12hrs and 24hrs—

Secondary

MeasureTime frame
to compare severity of post operative sore throat and hoarse ness of voiceTimepoint: 2 hours, 6 hours, 12 hours, 24 hours—

Countries

India

Contacts

Public ContactDR MANJUSHA M

MANDYA INSTITUTE OF MEDICAL SCIENCES

drumeshnp@gmail.com9886645947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026