Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: Narrow Band UVB: The study patients will be treated with whole body NBUVB phototherapy unit, administered thrice a week on alternate days. An initial dose of 200 mJ/cm2 will be administ
Sponsors
Keshavamurthy Vinay
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of non-segmental vitiligo involving 10-50% of body surface area 2. Age 12-60 years 3. Unstable disease, defined as occurrence of new lesion(s), progression of existing lesion(s) or Koebnerization 4. Should have received corticosteroids in any dose for >3 months
Exclusion criteria
Exclusion criteria: 1. Patients of segmental vitiligo and universal vitiligo 2. Contraindication to use of NBUVB phototherapy including xeroderma pigmentosa, systemic lupus erythematosus and other photo-induced or photo-aggravated dermatoses 3. Intake of phototoxic drugs 4. History of skin malignancy, premalignant skin lesions and dysplastic naevi 5. Claustrophobia 6. Hepatic and renal dysfunction 7. Immunosuppression 8. Associated connective tissue diseases including but not limited to systemic lupus erythematosus, rheumatoid arthritis 9. Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Measurement of bone mineral density using dual-energy X-ray absorptiometry (DEXA) at baseline and after 24 weeks. 2. Measurement of serum vitamin D levels at baseline and after 24 weeksTimepoint: Baseline 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NoneTimepoint: None | — |
Countries
India
Contacts
Public ContactKeshavamurthy Vinay
Post Graduate Institute Of Medical Education And Research, Chandigarh
Outcome results
None listed