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Study on the effect of citicoline in strengthening the loose fixation in Total hip replacement.

Comparative study on the effect of citicoline versus calcium in aseptic loosening in total hip arthroplasty - NA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050753
Enrollment
30
Registered
2023-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M253- Other instability of joint

Interventions

Intervention1: Citicoline: One group of patients with aseptic loosening of the components following total hip replacement receiving citicoline 1000mg orally every day for six months will be compared w

Sponsors

Pushpagiri Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Radiological evidence of loosening of any component 2. Symptomatic due to loosening 3.Those willing to participate 4.Patients not willing for revision surgery 5. Patients not fit for revision

Exclusion criteria

Exclusion criteria: 1.Smokers and Alcoholics not willing to stop the habits 2.Patients not tolerating citicoline and calcium 3.Patients on steroids and immunosuppresors 4.Diabetics, Renal and Hepatic failure 5.Immunodeficient patients 6. Any evidence of infection

Design outcomes

Primary

MeasureTime frame
disappearance of pain ,limping and radiologicalfeatures of looseningTimepoint: Clinical and radiological evidence of disappearance of loosening at 3,6,9 and 12 months—

Secondary

MeasureTime frame
Painless and stable hipTimepoint: three monthly evaluation untilll one year—

Countries

India

Contacts

Public ContactDrJohn PS

Pushpagiri Institute of Medical Sciences

drpsjohn@gmail.com9995060002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026