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The effect of different time interval between Fentanyl, a pain medication, and Thiopentone, an drug used to start anesthesia which helps in making the patient unconscious on total dose of the drug, Thiopentone.

Effect of varying time interval between Fentanyl and Thiopentone on total dose of Thiopentone used for induction of anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050751
Enrollment
210
Registered
2023-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Varying time interval: The intervention is the different time intervals between fentanyl and thiopentone at 1,3,5 mins and the effect on the total dose of thiopentone

Sponsors

VMMC and Safdarjung Hospital
Lead Sponsor
Ameeta Sahni
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adults of ASA II and II undergoing elective surgery under General Anaesthesia

Exclusion criteria

Exclusion criteria: Patients with allergy to thiopentone, and fentanyl. Patients with acute intermittent porphyria. Patients on anti- hypertensive medications and with history of chronic alcohol or drug use

Design outcomes

Primary

MeasureTime frame
To determine the effect of varying time interval between fentanyl and thiopentone on the total dose of thiopentone required for induction of anaesthesiaTimepoint: To determine the effect of varying time interval at 1,3,5 minutes between fentanyl and thiopentone on the total dose of thiopentone—

Secondary

MeasureTime frame
To determine the effect of varying time interval between fentanyl and thiopentone on the hemodynamic parameters following induction with thiopentone at 0, 3, 5 minsTimepoint: To determine the effect of varying time interval between fentanyl and thiopentone on the hemodynamic parameters following induction with thiopentone at 0, 3, 5 mins—

Countries

India

Contacts

Public ContactHarshita

Vardhman Mahavir Medical College and Safdarjung Hospital

ameetaas@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026