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Effect of Fluoride Varnish in preventing Dental Caries among young cancer patients

Effectiveness of Fluoride Varnish in preventing Dental Caries among paediatric patients undergoing Chemotherapy: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050718
Enrollment
60
Registered
2023-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: fluoride varnish: fluoride varnish will be applied on teeth at baseline, 3 month, 6month, 9month, 12 month Frequency: 5 fluoride application in a duration of a year. the duration is 1 y

Sponsors

Dr Vishesh Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Paediatric patient undergoing chemotherapy of age group 2-13 years with at least 4 teeth in the oral cavity 2. Willing to participate in the study

Exclusion criteria

Exclusion criteria: • Patient undergoing Radiotherapy along with chemotherapy. • Ulcerative gingivitis and stomatitis (trench mouth) • Any other disease

Design outcomes

Primary

MeasureTime frame
1.Initial Caries using ICDAS II scoring criteria. ICDAS II systems have two-digit coding for detection criteria of primary coronal caries. The first one is related to the restoration of teeth and has coding that ranges from 0 to 9. The second digit ranges from 0 to 6 which is used for coding caries. 2.DMFS/defs for progression of the disease, restoration and missing teeth. The DMFS/defs is a discrete quantitative variable ranging from 0-128 for permanent teeth. The mean DMFS/defs is a continuous quantitative variable of an individual. 3.Qualitative data will be recorded using dichotomous values as absent or present for incipient caries. Timepoint: baseline 3month 6months 12month

Secondary

MeasureTime frame
1. Missing teeth due to any other reason. 2. Filled teeth 3. Any anomalies occurring due to chemotherapy. Timepoint: baseline 3month 6months 12month

Countries

India

Contacts

Public ContactDr Kalpana Bansal

AIIMS

drharshpriya@gmail.com9953428936

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026