Health Condition 1: F445- Conversion disorder with seizuresor convulsions
Conditions
Interventions
Intervention1: Continuous theta burst stimulation: cTBS will be delivered over SMA for 2 sessions daily for any 5 days of a week for 1 week
Control Intervention1: Placebo: placebo treatment will be
Sponsors
Sri Guru Ram Rai Institute Of Medical And Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient with a diagnosis of FND-S, based on the diagnostic criteria of diagnostic and statistical manual of mental disorder, fifth edition (DSM 5) or international classification of disease (ICD 11) and confirmed by video EEG monitoring or video monitoring. 2.Patient aged between 15-59 years. 3.Patient with diagnosis of PNES with monthly frequency of >3 seizures (for at least a month). 4.Patient giving written consent to participate in protocol. For an adolescent, sample consent will be taken from the guardian. 5.Normotensive patients. 6.Patients not receiving any psychotherapy in last one month.
Exclusion criteria
Exclusion criteria: 1.Patient is uncooperative for the procedure. 2.Patient with history of previous or current epilepsy 3.Patients receiving ECT in past 6 months. 4.Patient with severe mental disorders (SMD). 5.Patient with implanted metallic devices. 6.Any co morbid substance use disorders except nicotine and caffeine (as per DSM 5). 7. Patient with other neurovascular comorbidities (tumor,cerebrovascular events (CVE), cranio-encephalic trauma. 8.Significant unstable medical condition like uncontrolled hypertension, complicated diabetes mellitus or any organ failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of dissociative symptoms - PNES SCORE,DESTimepoint: PNES SCORE , DES will be applied at baseline, 7th day and 21st day | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the quantitative change in depressive and anxiety symptoms in patients suffering from functional neurological symptom disorder, seizure type following active continuous theta burst stimulation compared with sham stimulation. To study the correlation among changes if any in dissociative, socio-demographic variables, depression, anxiety scores and other clinical measures following active continuous theta burst stimulation in patients suffering from functional neurological symptom disorder, seizure typeTimepoint: HADS, CGI, WHO-QOL BREF will be applied at baseline, 7th day and 21st day | — |
Countries
India
Contacts
Public ContactDr Ayushi Gera
Sri Guru Ram Rai Institute of Medical and Health Sciences
Outcome results
None listed