Skip to content

A controlled trial to study effect of Proprioceptive Neuromuscular Facilitation exercises on improving Lower limb sensorimotor function, balance and quality of life in chemotherapy induced peripheral neuropathy in gynecological cancer

Effect of Proprioceptive Neuromuscular Facilitation Technique and TENS on Lower Limb sensorimotor Function, Balance and Quality of life in Chemotherapy Induced Peripheral Neuropathy in Gynecological Cancer â?? A Randomized Control Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050705
Enrollment
46
Registered
2023-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G652- Sequelae of toxic polyneuropathy

Interventions

Intervention1: Proprioceptive Neuromuscular Facilitation Technique Along with Transcutaneous Electrical Nerve Stimulation: After identifying the area with pain the TENS will be applied along the distr

Sponsors

Datta Meghe Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Newly diagnosed patient with stages I to III gynecologic cancers including ovarian, uterine, and cervical cancer planning to receive definitive number of platinum based compounds chemotherapy. 2) Patients who are given Taxanes and Platinum based compounds â?? Cisplastin, Carboplatin and Oxaliplatin 3) Patients having Grade I or II peripheral neuropathy according to National Cancer Institute â??common toxicity criteria 4) Planned to receive a minimum of 4 cycles of chemotherapy treatment with either of the chemotherapy agents (Platinum based compound) 5) Women between 50 to 70 years.

Exclusion criteria

Exclusion criteria: 1) Male Patient 2) Patients having Pre existing peripheral nerve injury. 3) Patient with Type 2 Diabetes Mellitus ,Autoimmune and Inflammatory disorders 4) Patient having Grade III, IV, V peripheral neuropathy according to National Cancer Institute â?? common toxicity criteria suggesting that patient requiring assistive device are excluded. 5) Previous exposure to any of the implicated chemotherapy agents within last 5 years that could potentially cause peripheral neuropathy. 6) Stage IV cancer 7) Patients having any metal implants. 8) Patients with Artificial Pacemaker. 9) Patient having any traumatic Injury to the lower limb.

Design outcomes

Primary

MeasureTime frame
1)Shortened and Revised Total Peripheral Neuropathy Scale 2)Berg Balance Scale 3)Functional Assessment of Cancer Therapy/Gynecologic Oncology Group â?? Neurotoxicity Questionnaire Timepoint: Outcome Measure Will be assessed after 8 weeks of protocol and follow up will be taken after 3 weeks of completion of Intervention

Secondary

MeasureTime frame
1) Visual Analog Scale 2) Semmes Weinstein Monofilament test Timepoint: Outcome Measure Will be assessed after 8 weeks of protocol and follow up will be taken after 3 weeks of completion of Intervention

Countries

India

Contacts

Public ContactNikita Seth

Datta Meghe Institute of Higher Education and Research

irshadphysio@rediffmail.com09406010010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026