Health Condition 1: G652- Sequelae of toxic polyneuropathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Newly diagnosed patient with stages I to III gynecologic cancers including ovarian, uterine, and cervical cancer planning to receive definitive number of platinum based compounds chemotherapy. 2) Patients who are given Taxanes and Platinum based compounds â?? Cisplastin, Carboplatin and Oxaliplatin 3) Patients having Grade I or II peripheral neuropathy according to National Cancer Institute â??common toxicity criteria 4) Planned to receive a minimum of 4 cycles of chemotherapy treatment with either of the chemotherapy agents (Platinum based compound) 5) Women between 50 to 70 years.
Exclusion criteria
Exclusion criteria: 1) Male Patient 2) Patients having Pre existing peripheral nerve injury. 3) Patient with Type 2 Diabetes Mellitus ,Autoimmune and Inflammatory disorders 4) Patient having Grade III, IV, V peripheral neuropathy according to National Cancer Institute â?? common toxicity criteria suggesting that patient requiring assistive device are excluded. 5) Previous exposure to any of the implicated chemotherapy agents within last 5 years that could potentially cause peripheral neuropathy. 6) Stage IV cancer 7) Patients having any metal implants. 8) Patients with Artificial Pacemaker. 9) Patient having any traumatic Injury to the lower limb.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Shortened and Revised Total Peripheral Neuropathy Scale 2)Berg Balance Scale 3)Functional Assessment of Cancer Therapy/Gynecologic Oncology Group â?? Neurotoxicity Questionnaire Timepoint: Outcome Measure Will be assessed after 8 weeks of protocol and follow up will be taken after 3 weeks of completion of Intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Visual Analog Scale 2) Semmes Weinstein Monofilament test Timepoint: Outcome Measure Will be assessed after 8 weeks of protocol and follow up will be taken after 3 weeks of completion of Intervention | — |
Countries
India
Contacts
Datta Meghe Institute of Higher Education and Research