Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Patients in HPI group will be monitored with EV 1000 HPI monitor (Edwards
Lifescience) and management will be done as per study protocol: Duration : Intraoperative period (during renal
Sponsors
Kamal Kajal
Eligibility
Inclusion criteria
Inclusion criteria: Written informed consent End-stage renal disease patients scheduled for renal transplant surgery
Exclusion criteria
Exclusion criteria: Refusal of consent Surgery without controlled ventilation or ony Regional anaesthesia Contraindication to invasive blood pressure monitoring Atrial fibrillation Pregnancy Massive Ascites Patients with underlying Respiratory Failure Heart Failure Known clinically intracardiac shunts and severe valvular heart disease. Patient with ongoing active infection Deceased Renal transplants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time weighted average mean arterial pressure less than 65 mmHgTimepoint: Every 5 Minutes interval | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of immediate graft dysfunction Incidence of delayed graft function Creatinine elimination ratio at 72 hours Ability of static parameters like CVP in predicting Hypotension events Ability of dynamic indices like PPV in predicting Hypotensive events Hospital stay and intensive care unit stay Perioperative fluid intake and blood loss Concentration of serum troponin at baseline and day 1 postoperative Vasopressors and inotropic medication used Survival at day 90 after surgeryTimepoint: immediately after surgery 24 hours and 7 days after surgery 72 hours after surgery every 5 minutes during surgery every 5 minutes during surgery 30 days and 90 days after surgery every 1 hour during surgery after 24 hours of surgery every hour during and after surgery 90 days after surgery | — |
Countries
India
Contacts
Public ContactKamal Kajal
PGIMER, Chandigarh
Outcome results
None listed