Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Bupivacaine plus dexmedetonidine: 2mg/kg of 0.25% bupivacaine plus 1microgram/kg of dexmedetomidine will be infilterated in scalp before skin incision and pin insertion and will observe
Sponsors
PGIMS Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: Patients belonging to American Society of Anesthesiologists (ASA) physical status I, II & III, scheduled to undergo craniotomy for tumor, aneurysm, tuberculoma, to remove epileptic focus etc. and who are able to understand the study protocol will be included in the study.
Exclusion criteria
Exclusion criteria: The patients who ï?¬ History of hypertension, diabetes mellitus and cardiovascular disease ï?¬ Local anaesthetic allergy ï?¬ Allergy to dexmedetomidine ï?¬ are not willing to give consent will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of scalp infiltration of bupivacaine and bupivacaine plus dexmedetomidine before skin incision and pin insertion on heart rate and mean arterial pressure.Timepoint: Heart rate and blood pressure will be recorded at Eight time points: 1) At baseline after the induction of anesthesia; 2) after pin insertion; 3) after scalp incision; 4) during dural opening 5) during dural closure; 6) during skin closure; 7) on admission to the post aneasthesia care room (PACU); and 8) 2 h after admission to the PACU. | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe side effects of the study drugs used.Timepoint: At any point of time intraoperatively and postoperatively | — |
Countries
India
Contacts
Public ContactGeeta Choudhary
PGIMS Rohtak
Outcome results
None listed