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effect of two different doses of intraspinal morphine for post caesarean analgesia

A comparative study on the analgesic effects of two different doses of morphine added to intrathecal levobupivacaine in Caesarean section: a randomised double-blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050622
Enrollment
76
Registered
2023-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: intrathecal morphine 50 mcg added to levobupivacaine: Group A will receive 10mg of intrathecal Hyperbaric Levobupivacaine (0.5 %) with 50 mcg morphine. Intrathecal injection will take 5

Sponsors

AIIMS Bibinagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and ASA grade 2 single-foetus pregnancy, age between 20-35 YRS more than 37 weeks of gestational age scheduled for elective caesarean section

Exclusion criteria

Exclusion criteria: Emergency surgeries ASA grade 3,4,5 Known bleeding diathesis Neuromuscular disease Local skin infections/Contraindications to neuraxial anaesthesia Body mass index greater than 40 kg/m2 Allergy to any of the study medications Patients on psychiatric or chronic pain medication

Design outcomes

Primary

MeasureTime frame
Time to first analgesic request: time between administration of intrathecal morphine and the request of first rescue analgesia in the postoperative period.Timepoint: 4hours,8hours,12hours,24hours after surgery

Secondary

MeasureTime frame
Maternal side effects: Incidences of nausea or vomiting, need for anti-emetics, incidence of pruritus and need for medication, will be recorded for 24 hrs after surgeryTimepoint: secondary outcomes will be recorded at 3,6,12 and 24 hour after surgery for 24 hours

Countries

India

Contacts

Public ContactAyya Syama Sundar

AIIMS Bibinagar, Hyderabad

sasyasyama@gmail.com08179309677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026