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Effectiveness of Simvastatin for bone regeneration in an extraction socket

Evaluation of efficiency of Simvastatin on Bone Regeneration in an Extraction socket: A Split-mouth Randomized controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050618
Enrollment
20
Registered
2023-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: CASE GROUP: Dose : 10mg Frequency : only once Route of administration: locally (topically) in the extraction socket Simvastatin along with gelatin sponge in an extraction socket. 10mg

Sponsors

Swargiya Dadasaheb kalmegh smruti dental college and hospital
Lead Sponsor
DrAlvina Khan
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients between age of 18-60 years. Participants of both genders i.e. males and females. Patients indicated for intra-alveolar extraction of teeth under LA.

Exclusion criteria

Exclusion criteria: Medically compromised patients. Patients having radiographical periapical changes (Abscess,Granuloma,Cyst) Patients having OSMF. Teeth requiring transalveolar or open extraction. Generalized/Localised Periodontitis Smokers and Alcoholics Pregnant women History of radiotherapy in the head and neck region.

Design outcomes

Primary

MeasureTime frame
To compare and evaluate bone regeneration with or without simvastatin along with gelatin sponge as a carrier in an extraction socketTimepoint: Evaluation of bone density will be assessed at baseline that is immediately after extraction and after 8 weeks and 16 weeks—

Secondary

MeasureTime frame
NATimepoint: NA—

Countries

India

Contacts

Public ContactDr Manu Goel

Swargiya dadasaheb kalmegh smruti dental college and hospital wanadongri hingna nagpur

manu.goel@sdk-dentalcollege.edu.in9011794068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026