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A CLINICAL TRIAL TO STUDY THE EFFECTS OF 2 DRUGS, CARBETOCIN AND OXYTOCIN ON PREVENTION OF POSTPARTUM BLOOD LOSS

COMPARISON OF CARBETOCIN versus OXYTOCIN FOR PROPHYLAXIS OF ATONIC POSTPARTUM HEMORRHAGE â?? A RANDOMIZED CONTROL STUDY

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050602
Enrollment
214
Registered
2023-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O720- Third-stage hemorrhage

Interventions

Intervention1: IM OXYTOCIN AND ITS ANALOGUE PREPARATION: WOMEN UNDERGOING VAGINAL DELIVERY WITH ATLEAST ONE RISK FACTOR FOR DEVELOPING ATONIC POSTPARTUM HEMORRHAGE WILL BE TREATED WITH INJECTABLE OXYT

Sponsors

BPS GOVT. MEDICAL COLLEGE FOR WOMEN , KHANPUR KALAN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Term pregnancy (37 weeks to 40 weeks) Cephalic presentation Atleast one risk factor for developing atonic PPH- uterine overextension (macrosomia , polyhydroamnios , multiple pregnancy) prolonged labor Anemia (Hb Previous history of PPH Grand multipara Labor induction or augmentation with oxytocin Pregnancy complications like hypertension , gestational diabetes

Exclusion criteria

Exclusion criteria: Patients undergoing Cesarean section Traumatic & other causes of PPH Instrumental Delivery Coagulation Disorders Antepartum Hemorrhage (placenta previa , abruptio) HELLP and Eclampsia Precipitate Labor History of any cardiac , renal , liver disease , epilepsy Patients who have respiratory problems Eg : Asthmatics Known allergies to oxytocin and/or carbetocin Those without risk factor Refused to participate in the study

Design outcomes

Primary

MeasureTime frame
efficacy of both drugs in preventing atonic post partum hemorrhageTimepoint: 2 hours post delivery

Secondary

MeasureTime frame
mount of blood loss during delivery , effects on Hemoglobin values pre and post delivery , safety and side effects of treatment Timepoint: 24 hours post delivery

Countries

India

Contacts

Public ContactDR KIYOSHI DHANKHAR

BPS GMC FOR WOMEN , KHANPUR KALAN , SONEPAT

dr.rmahendru@gmail.com9416086483

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026