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Comparison of dexmedetomidine with Ropivacaine 0.1% and buprenorphine with ropivacaine 0.1% for post operative epidural analgesia to reduce pain in lower limb orthopaedic surgeries done under spinal anesthesia block

Comparison of dexmedetomidine and buprenorphine as adjuvant to ropivacaine 0.1% for post operative epidural analgesia in lower limb orthopaedic surgeries done under spinal anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050571
Enrollment
60
Registered
2023-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Epidural catheter insertion and drug comparison between ropivacaine- Buprenorphine and ropivacaine- dexmedetomidine: Drugs used - Ropivacaine 0.1%, dexmedetomidine(1mcg/ml), Buprenorphi

Sponsors

Mahatma Gandhi medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-65yrs ASA grade 1&2 Elective lower limb orthopaedic surgery Who have given valid informed consent.

Exclusion criteria

Exclusion criteria: Patients with heart block, bradyarrythmia and Left ventricular failure Bleeding or coagulation abnormalities Severe renal disease Severe Liver dysfunction

Design outcomes

Secondary

MeasureTime frame
Heart rate , mean blood pressure , patient satisfactionTimepoint: Post operatively for 24 hrs—

Primary

MeasureTime frame
Pain assessment , hemodynamic changes and motor assessmentTimepoint: 2hrly—

Countries

India

Contacts

Public ContactDr Kalpana Verma

Mahatma Gandhi hospital

drrcgupta@mgumst.org9001896578

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026