Dental caries removing agent prepared from pineapple extraction on patient mouth and Lab study

Preparation of Ananas Comosus (Pineapple) Extract based Chemomechanical Caries removal agent and Assessment of its in-vitro and in-vivo efficiency

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050528

Enrollment

Registered

2023-03-09

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ananas Comosus Extract: Pineapple Extract Control Intervention1: Enzyme based Chemo-mechanical Caries removal agent: Traditional - Chemo-mechanical Caries removal agent

Eligibility

Inclusion criteria

Inclusion criteria: Part 1: Invitro study - Freshly extracted human teeth with carious lesion extending into dentin Part 2: Invivo study - Mentally sound children aged 6 â?? 12 years - Children with bilateral caries lesion involving the dentin (ICDAS code 4 or 5) - Children whose parents given consent to participate in the study - Children who give assent to participate in the study

Exclusion criteria

Exclusion criteria: Part 1: Invitro study - Teeth with development defects - Teeth with hypoplastic defects including Molar- Incisor Hypomineralization, dental fluorosis Part 2: Invivo study - Children with development defects of the teeth - Children with extensive caries involving the pulp

Design outcomes

Primary

Measure	Time frame
Based on the results of the present study, a new product can be developed which can be a value addition to the armamentarium of dentist practicing minimal invasive dentistry. The test product can be more specific in removal of carious tissue without causing any damage to the underlying sound tooth structure unlike the control product which is non-specific in action. Additionally, the product has the scope of being patented.Timepoint: 6 months - 1 year	—

Measure

Time frame

Based on the results of the present study, a new product can be developed which can be a value addition to the armamentarium of dentist practicing minimal invasive dentistry. The test product can be more specific in removal of carious tissue without causing any damage to the underlying sound tooth structure unlike the control product which is non-specific in action. Additionally, the product has the scope of being patented.Timepoint: 6 months - 1 year

—

Secondary

Measure	Time frame
Based on the results of the present study, a new product can be developed which can be a value addition to the armamentarium of dentist practicing minimal invasive dentistry. The test product can be more specific in removal of carious tissue without causing any damage to the underlying sound tooth structure unlike the control product which is non- specific in action. Additionally, the product has the scope of being patented.Timepoint: 1 year	—

Measure

Time frame

Based on the results of the present study, a new product can be developed which can be a value addition to the armamentarium of dentist practicing minimal invasive dentistry. The test product can be more specific in removal of carious tissue without causing any damage to the underlying sound tooth structure unlike the control product which is non- specific in action. Additionally, the product has the scope of being patented.Timepoint: 1 year

—

Countries

India

Contacts

Public ContactDr Manoj Kumar

Meenakshi Academy of Higher Education and Research

mjdentsg@gmail.com7401277273

Outcome results