Effect of supraglottic and subglottic addition of dexamethasone or dexmedetomidine for postoperative sore throat after general anaesthesia

efficacy of supraglottic and subglottic instillation of dexamethasone or dexmedetomidine for the incidence and severity of postoperative sore throat after general anaesthesia

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050517

Enrollment

130

Registered

2023-03-09

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K318- Other specified diseases of stomach and duodenum

Interventions

Intervention1: supraglottic and subglottic instillation of dexamethasone: supraglottic and subglottic instillation of dexamethasone 8mg diluted in normal saline to 5ml after intubation. patients will

Eligibility

Inclusion criteria

Inclusion criteria: VALID CONSENT , ASA 1 AND 2 , MALLAMPATTI CLASS 1 & 2 , POSTED FOR SURGERY UNDER GENERAL ANAESTHESIA

Exclusion criteria

Exclusion criteria: REFUSAL , ASA 3 OR MORE , AGE LESS THAN 18 YRS AND MORE THAN 65 YRS , HISTORY OF UPPER RESPIRATORY TRACT SENSITIVITY AND SORE THROAT , PREGNANCY , MORBID OBESITY , ICU TRANSFERRED PATIENTS WITH E.T TUBE IN SITU

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of supraglottic and subglottic Instillation of dexamethasone verses dexmedetomidine in decreasing the incidence and severity of post operative sore throat (POST) after general anaesthesia.Timepoint: 0, 2 hr, 4 hr, 6 hr, 12 hr, 24 hr	—

Secondary

Measure	Time frame
To assess the post operative hemodynamic stability, Pain on deglutition, Hoarseness, Cough or any other adverse effects.Timepoint: 0 , 2 hr , 4 hr , 6 hr , 12 hr , 24 hr	—

Countries

India

Contacts

Public Contactsanjay kumar

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES,PATNA -14

drhussain72@yahoo.co.in9473376853

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026