To study the effects of a Unani formulation in patients with Acne.

Evaluating the therapeutic effects of a Unani Formulation of Lattukh (smear) in the management of Buthur Labaniyya (Acne vulgaris): A single blind, randomized, standard control study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050493

Enrollment

Registered

2023-03-09

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Lattukh (Smear): It is a classical Unani formulation taken from Canon of Medicine. The formulation comprises of Injir (Ficus carica Linn) (dried fruit), Kalonji (Nigella sativa) (seeds)

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of age between 12-40 years. 2) Patients with mild to moderate forms of acne. 3) Irrespective of gender. 4) Patients with itching, erythema, comedones, papules and pustules. 5) Patients who are willing to give consent and are able to follow up.

Exclusion criteria

Exclusion criteria: 1) Patients below 12 years and above 40 years of age. 2) Patients with severe forms of acne. 3) Diagnosed patients of PCOS. 4) Pregnant and lactating women. 5) Patients on corticosteroid therapy and on OCPâ??s. 6) Patients suffering from systemic illnesses like Cardiovascular disease, chronic kidney disease and chronic liver disease, thyroid disease or malignancy.

Design outcomes

Primary

Measure	Time frame
1) Change from baseline to day 41st in the inflammatory (Papules and pustules) lesions and non-inflammatory (open and closed comedones) lesions (GAGS- Global Acne Grading System). 2) Change from baseline to day 41st in Investigatorâ??s Global Assessment of Acne (IGA). 3) Change from baseline to day 41st day in the inflammatory (papules and pustules) lesions based on photographs of lesions. 4) Change from baseline to day 41st day in the quality of life of subjects based on the Dermatology Life Quality Index (DLQI). Timepoint: 40 days.	—

Measure

Time frame

1) Change from baseline to day 41st in the inflammatory (Papules and pustules) lesions and non-inflammatory (open and closed comedones) lesions (GAGS- Global Acne Grading System). 2) Change from baseline to day 41st in Investigatorâ??s Global Assessment of Acne (IGA). 3) Change from baseline to day 41st day in the inflammatory (papules and pustules) lesions based on photographs of lesions. 4) Change from baseline to day 41st day in the quality of life of subjects based on the Dermatology Life Quality Index (DLQI). Timepoint: 40 days.

—

Secondary

Measure	Time frame
1)Effect on itching based on Visual Analogue Scale (VAS). 2) Effect on redness based on Clinical Erythema Assessment (CEA). 3) Effect on eruptions based on Simple Grading System by Indian Authors.Timepoint: 40 Days.	—

Countries

India

Contacts

Public ContactDr Zaffar Hussain

Regional Research Institute of Unani Medicine (RRIUM), Srinagar

hussainzaffar6@gmail.com7006021996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026