FindTrial
Sign In

Combination of chest wall nerve blocks for reducing heart rate, blood pressure and acute pain during breast cancer surgeries: a prospective interventional randomized controlled trial

Combination of pectoral nerve block I (PECS I) and serratus anterior plane block (SAP) for attenuation of intraoperative surgical stress response and postoperative acute pain management during modified radical mastectomy: a prospective interventional randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050487
Enrollment
36
Registered
2023-03-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Combination of pectoral nerve block I (PECS I) and serratus anterior plane block (SAP) using 0.25% bupivacaine 10 ml and 25 ml respectively.: Inside the operating room after securing t

Sponsors

Dr Monotosh Pramanik
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a.American Society of Anesthesiologists (ASA) I-II patients. b.Aged between 18â??65 years. c.Female patients undergoing post-chemotherapy unilateral modified radical mastectomy with complete axillary clearance.

Exclusion criteria

Exclusion criteria: a.Patient refusal and patient unable to give valid consent. b.Patient undergoing supraclavicular lymph node dissection. c.Pregnant patients. d.Known hypersensitivity to local anesthetics e.Infection at the site of injection and f.History of chronic analgesic use.

Design outcomes

Primary

MeasureTime frame
1.Intraoperative fentanyl requirement to reduce autonomic response due to surgical stimulus 2.Postoperative Visual Analog Scale (VAS) pain score.Timepoint: 1.Total fentanyl requirement at the end of surgical procedure. 2.VAS pain score at 30 minutes interval till 2 hours postoperatively.—

Secondary

MeasureTime frame
1.Intraoperative vitals. 2.Postoperative analgesic use in the recovery room 3.Incidence of postoperative nausea vomiting (PONV) Timepoint: 1. Mean of intraoperative vitals at the end of surgical procedure. 2. Total analgesic requirement postoperatively during the recovery room stay for 2 hours postoperatively. 4. occurrence of PONV during the recovery room stay for 2 hours postoperatively.—

Countries

India

Contacts

Public ContactMONOTOSH PRAMANIK

MAHAMANA PANDIT MADAN MOHAN MALAVIYA CANCER CENTRE AND HOMI BHABHA CANCER HOSPITAL

mpramanikforyou@gmail.com8413044039

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026