Health Condition 1: L438- Other lichen planus
Conditions
Interventions
Intervention1: CYCLOSPORINE: Cyclosporine is a nonmyelotoxic immunosuppressant whose primary target is the helper/inducer T lymphocyte. By inhibiting the helper/inducer T cells, cyclosporine may inter
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy adults aged between 18 to 60 years. 2.Symptomatic patients having only Oral involvement of Lichen Planus which is biopsy proven and has not responded to any topical therapy for 3 months.(ODSS score >30)
Exclusion criteria
Exclusion criteria: 1.Patients having extraoral involvement of Lichen Planus and erosive type of Lichen Planus 2.Patients with uncontrolled or severe hypertension, diabetes mellitus 3.Patients with active or recurrent infections, severe respiratory, renal, hepatic or heart disease 4.Patients with underlying endocrine or hematopoietic disorders 5.Patients who have a habit of tobacco chewing, beetle nut chewing and smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of Oral Cyclosporine vs Oral Steroid in the treatment of Oral Lichen Planus.Timepoint: At baseline,a monthly follow up of the patient for three months ,followed by 2 monthly visits for the next 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of Oral Cyclosporine vs Oral Steroid in the treatment of Oral Lichen PlanusTimepoint: At the end of follow up,that is at 9 months. | — |
Countries
India
Contacts
Public ContactADITHYA PRAKASH
Ims and Sum Hospital
Outcome results
None listed