Health Condition 1: - Health Condition 2: N461- Oligospermia Health Condition 3: N468- Other male infertility
Conditions
Interventions
Intervention1: Lifestyle intervention: Customized advice on diet and physical exercise will be given.Those engaged in sedantary / less physical activity will be advised to walk for at least 30 minutes
Sponsors
Christian Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Men with idiopathic oligozoospermia or/and asthenozoopsermia or oligoathenozoopspermia or oligoasthenozooteratozoospermia. Age >21 years and
Exclusion criteria
Exclusion criteria: Men who are unable to come up for follow up. Men from states other than Tamil Nadu, Karnataka, Kerala, Andhra Pradesh & Telangana Men who smoke Men with clinically palpable varicocoele Men who are on drugs which are known to affect spermatogenesis Men who are on antioxidants supplements within previous six months. Men with azoospermia or cryptozoospermia Men with sperm concentration of Men with previous history of childhood mumps, gonadotoxic therapy or immunosuppressants intake. Surgical history of orchidectomy/ other genitourinary surgery like varicocoelectomy, testicular torsion Men with recent intake of alternative modalities of treatment (Ayurvedic/ Homeopathy within 6 months GI conditions such as Ulcerative colitis, Crohns disease which have special dietary advice Men with Diabetes mellitus, chronic renal disease, malignancy, sexually transmitted disease Female partner with other known causes of infertility as below: Severe endometriosis Documented tubal bilateral pathology Endometrial pathology such as Ashermanâ??s syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of participants completing the intervention (dropout rate)Timepoint: At the end of six months | — |
Secondary
| Measure | Time frame |
|---|---|
| Noncompliance rate Improvement in semen parameters Reason (s) for refusal to participate in the trial Reason (s) for refusal to be randomized after initially agreeing to participate in the trial Reason (s) for drop out (discontinuation of the lifestyle intervention i.e. customized diet / exercise advise) Reason (s) for noncompliance to the lifestyle intervention i.e. customized diet/exercise Improvement in DNA Fragmentation Index Biomarker level (Total plasma antioxidant capacity) Clinical pregnancy rate (per couple) Miscarriage rate (per couple) Timepoint: At the end of six months | — |
Countries
India
Contacts
Public ContactDr Mohan S Kamath
Christian Medical College and Hospital
Outcome results
None listed