Health Condition 1: C569- Malignant neoplasm of unspecifiedovary
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
International Atomic Energy Agency (IAEA)
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Patients with histologically proven diagnosis of ovarian carcinoma 2. Peritoneal carcinomatosis known or with high suspicion, without known further metastatic spread, before undergoing debulking surgery 3. 18F-FDG PET/CT performed prior to surgery less than 4 weeks 4. Signature of informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Metastatic disease known apart from peritoneal carcinomatosis 2. Diabetic patients with bad control 3. Debulking surgery not indicated 4. Surgical contraindications 5. Unable to consent 6. Estimated glomerular filtration rate (eGFR) 7. Claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the diagnostic performance of 18F-FDG PET/CT and its comparison to conventional imaging for staging OC.Timepoint: Within 4 weeks before surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes include the assessment of prognostic value of different peritoneal carcinomatosis scoring systems and comparison with 18F-FDG PET/CT in ovarian cancer patients. Performance of different PET systems and inter reader agreement (using cohen’s kappa) will also be assessed.Timepoint: Post surgery follow up | — |
Countries
India
Contacts
Public ContactDr Harmandeep Singh
PGIMER
Outcome results
None listed