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The rationale of study is that which one among Nalbuphine and Buprenorphine,is a better adjuvant yet to be explored as only few studies happened in past on this

Hyperbaric Bupivacaine with Nalbuphine and Buprenorphine Intrathecally for Postoperative Analgesia in Lower Abdominal and Lower Limb Surgeries : A Randomised Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050389
Enrollment
60
Registered
2023-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Hyperbaric Bupivacaine with Nalbuphine intrathecally in Lower Abdominal and lower limb surgeries: 0.5% Bupivacaine hyperbaric (2.5 ml) and Nalbuphine 0.6 mg Control Intervention1: Hyper

Sponsors

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologists (ASA) grade 1 or 2 Posted for surgeries of lower abdomen or lower limb of different surgical specialities

Exclusion criteria

Exclusion criteria: Patient refusal for procedure Any Neuropathy,Cardiac disease,diabetes,Nephropathy,Coagulopathy Any known allergy to local anaesthetic Patients with contraindications for spinal anaesthesia such as derranged coagulation profile ,raised ICP,local infection at site of needle insertion

Design outcomes

Primary

MeasureTime frame
Onset of sensory and motor block Duration of sensory and motor block Duration of postoperative analgesia Timepoint: At 2,4,6,8,10,12,14,16,18,20,30,40,50,60,90,120,180,240,360,720 minutes after block , heart rate ,ECG lead 2 ,systolic , diastolic and mean blood pressure and oxygen saturation will be recorded

Secondary

MeasureTime frame
Hemodynamic responses to the drug during and after surgery Any complication or side effectsTimepoint: At 2,4,6,8,10,12,14,16,18,20,30,40,50,60.90,120,180,240,360,480,720 minutes after the block , heart rate ,ECG lead 2,systolic,diastolic and mean blood pressure and oxygen saturation will be recorded

Countries

India

Contacts

Public ContactDR DHARIWAL RAHUL GAJPAL SINGH

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL , BAREILLY

sarfaraz_ahm2000@yahoo.com7088833111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026