Health Condition 1: H268- Other specified cataract
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
AIIMS, Raipur
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for cases: 1. The patients with LOCS III cataract grading of nuclear >=4, cortical >=3, or posterior subcapsular >=2 in the worse eye. 2. Type 2 diabetes mellitus as per American Diabetic Association Criteria. Inclusion criteria for controls: 1. Subjects with cataract less than 4 for nuclear, less than 3 for cortical, and less than 2 for posterior subcapsular and no aphakia or pseudophakia in either of the eye. 2. Type 2 diabetes mellitus as per American Diabetic Association Criteria.
Exclusion criteria
Exclusion criteria: Exclusion criteria for cases and controls: Subjects with type 1 diabetes, gestational diabetes, and Maturity-onset diabetes of the young (MODY) will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify whether diabetic cataract in Indian population is associated with the 3 SNPs (rs11129182, rs17047573, and rs17047586) on chromosome 3p14.1- 3p14.2 locus, as identified in diabetic cataract in the Taiwanese population.Timepoint: one year | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify the correlation between duration of diabetes and SNP expression in cases of diabetic cataract.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Ankur K Shrivastava
AIIMS, Raipur
Outcome results
None listed