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PRE-ADMINISTRATION OF 50ML AND 100ML 6% HYDROXYETHYL STARCH FOR REDUCTION OF PAIN ON PROPOFOL INJECTION

Effect of pre-administration of 50ml and 100ml 6% hydroxyethyl starch for reduction of pain on propofol injection: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050378
Enrollment
180
Registered
2023-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pre-administration of 50ml or 100 ml 6% hydroxyethyl starch: Study participants will be randomized into three groups. Intervention group receiving either 50ml 6% hydroxyethyl starch or

Sponsors

Antony Xavier
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age group 18 to 60 years. (Dose adjustment of hydroxyethyl starch needed in paediatric and >60 years of age) 2. Patients of American Society of Anaesthesiologists (ASA) physical grade I or II.

Exclusion criteria

Exclusion criteria: 1. Patients with neurological deficits. 2. Patients with history of allergy 6% hydroxy ethyl starch and propofol. 3. Patients taking any analgesic before surgery. 4. Patients with diabetes, hypertension, cardiac disease, hepatic, renal, pulmonary disease and convulsion. 5. Patients with morbid obesity. 6. Patients with anticipated difficult venous access. 7. Patients with pregnancy and breastfeeding. 8. Patients with chronic pain syndromes. 9. Patients with disorders of lipid metabolism. 10. Patients having problems in communication.

Design outcomes

Primary

MeasureTime frame
Pain on propofol injectionTimepoint: Outcome will be assessed at the point of administration of propofol. Data will be then assessed at the end of one year.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactRupendra Singh Thokchom

Regional Institute of Medical Sciences, Imphal, Manipur

penbeeru63@gmail.com9774247043

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026