Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
None listed
Sponsors
ARYA DEVI S
Eligibility
Inclusion criteria
Inclusion criteria: a) Age group of 20 â?? 60 years of either sex. b) Patients with diagnosis of Type 2 Diabetes Mellitus, based on the parameters- fasting plasma glucose ( FPG) >= 126 mg/dl or 2 hour plasma glucose ( PG) >= 200 mg / dl, or HbA1C ( glycated haemoglobin ) >= 6.5 % or random plasma glucose >= 200 mg / dl, as per 2019 American Diabetes Association classification. c) Individuals with healthy periodontium, d) Patients with diagnosis of generalized stage III grade B periodontitis, as per 2017 World Workshop on classification of periodontal and peri-implant diseases and conditions. e) Individuals who smoke f) Presence of at least 20 natural teeth.
Exclusion criteria
Exclusion criteria: a) Patients with any systemic diseases other than Type 2 Diabetes Mellitus. b) Those who have undergone periodontal therapy in last six months preceding the start of the study. c) Individuals who have history of any antimicrobial or anti- inflammatory therapy in the last six months. d) Pregnant, lactating and postmenopausal women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To estimate the levels of sTREM-1 and TNF -α in GCF of subjects with health and generalized stage III grade B periodontitis with and without Type 2 Diabetes Mellitus. 2. To correlate the levels of sTREM-1 and TNF- α in GCF of subjects with health and generalized stage III grade B periodontitis with and without Type 2 Diabetes MellitusTimepoint: At baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 3. To explore the possibility of using sTREM-1 and TNF-α as a marker for health, Type 2 Diabetes Mellitus and generalized stage III grade B periodontitis and relate them with clinical parameters.Timepoint: At baseline | — |
Countries
India
Contacts
Public ContactArya Devi S
The Oxford Dental College
Outcome results
None listed