Health Condition 1: G968- Other specified disorders of central nervous system Health Condition 2: G968- Other specified disorders of central nervous system
Conditions
Interventions
Intervention1: Magnesium sulphate: Administration of magnesium sulphate infusion in craniotomy patients after induction till dura closure
Intervention2: nil: In control group patients undergoing crani
Sponsors
Dr Manoj Kumar Giri
Eligibility
Inclusion criteria
Inclusion criteria: ASA Grade 1 and 2 patients Elective craniotomies (both supratentorial and posterior fossa surgeries) GCS 15
Exclusion criteria
Exclusion criteria: ASA Grade III and IV Pregnant female Patients with neuromuscular renal cardiovascular 0r hepatic insufficiency BMI 24.9kg/m2 Allergy to the study drugs Those on treatment with calcium channel blockers or magnesium Patients who will be shifted on ventilator post craniotomy Anaesthesia time more than 5 hrs preventing excessive infusion of MgSO4 Any other mental or physical illness rendering them incapable of answering pain score Patient on any previous chronic pain medications like gabapentin or pregabalin Trauma and emergency craniotomies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of magnesium sulphate on reduction in post operative rescue analgesic requirement and post operative pain in the study groupTimepoint: start magnesium sulphate after induction till closure of dura.Post operative pain will be assessed at 1st hr 2nd hr 4th hr 6th hr 8th hr 12th hr 16th hr 20th hr and 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of MgSO4 on reduction of intraop dose of Propofol and Vecuronium during surgeryTimepoint: start magnesium sulphate after induction till closure of dura | — |
Countries
India
Contacts
Public ContactDr Nidhi Varma
DR RMLIMS
Outcome results
None listed