Health Condition 1: D644- Congenital dyserythropoietic anemia
Conditions
Interventions
None listed
Sponsors
Department of Transfusion Medicine GMCH-32
Eligibility
Inclusion criteria
Inclusion criteria: Male blood donors in the age group of 18-30 years and 45-65 years and meeting all other criteria for whole blood donation as per guidelines laid by Drug Controller General of India (DCGI). Thalassemia children receiving blood transfusions at Government Medical College and Hospital, Chandigarh only. Thalassemia children in the age group of 3-9 years.
Exclusion criteria
Exclusion criteria: Blood donors not meeting eligibility criteria laid down by the DCGI. Male donors between 31- 44 years of age. Female blood donors. Thalassemic children having - Clinical evidence of hypersplenism - Presence of auto antibody - Presence of unidentifiable alloantibodies - Fever / acute infection - Congestive Cardiac Failure (CCF) - If volume of transfusion required is 600ml.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â??Maintaining pre-transfusion haemoglobin of 9-10.5 g/dl. â??Number of donor exposures to the patient.Timepoint: â??Maintaining pre-transfusion haemoglobin of 9-10.5 g/dl after 3 weeks of transfusion. â?? Number of donor exposures to the patient after 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparing the iron overload in two groups by measuring the change in serum ferritin levels during the study period. Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactProf Ravneet Kaur
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh
Outcome results
None listed