A study to compare the efficacy of antiseptics Chlorhexidine alcohol vs Povidone Iodine alcohol in reducing bacterial colonisation by intravenous catheter in Paediatric ward in hospital

Comparative study of efficacy of Chlorhexidine alcohol vs Povidone Iodine alcohol in reducing peripheral venous catheter colonisation in Paediatric ward in a tertiary care center.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050292

Enrollment

102

Registered

2023-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A00-B99- Certain infectious and parasitic diseases Health Condition 2: Q00-Q99- Congenital malformations, deformations and chromosomal abnormalities Health Condition 3: D50-D89- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism Health Condition 4: I00-I99- Diseases of the circulatory system Health Condition 5: K00-K95- Diseases of the digestive system Health Condition 6: H60-H95- Diseases of the ear and mastoid process Health

Interventions

Intervention1: 2% CHLORHEXIDINE Alcohol: 2% CHLORHEXIDINE alcohol will be used for painting the part of the patient for 1 minute where peripheral line will be inserted. Control Intervention1: 10% Povi

Eligibility

Inclusion criteria

Inclusion criteria: 1.All Paediatric patient (1month -16 years) requiring admission in Paediatric ward. 2.Indication for PVC for at least 48 hours. 3.Parents willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Skin injury at catheter insertion sites. 2. Catheter inserted in emergency. 3. Known allergy to the chlorhexidine Or Povidone iodine. 4. Difficult insertion of catheter as in obese patient or repeat attempts. 5. Patients critically ill not expecting to survive more than a week 6. Not willing for the study.

Design outcomes

Primary

Measure	Time frame
Primary outcome will be incidence of catheter tip colonisation on culture.Timepoint: 1.Day 1 of admission - Peripheral venous catheter to be inserted after cleaning by either 2â?? chlorhexidine alcohol or 10â?? povidone iodine alcohol At end of 72 hrs -IV Catheter removed and catheter tip send for culture for colonisation	—

Secondary

Measure	Time frame
Secondary outcome will be incidence of Catheter occlusion, accidental catheter removal, catheter related blood stream infection, incidence of side effects related to type of antiseptic use.Timepoint: Within 72 hours	—

Countries

India

Contacts

Public ContactSham Lohiya

JNMC Sawangi

sham.lohiya19@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026