Health Condition 1: K044- Acute apical periodontitis of pulpal origin
Conditions
Interventions
Intervention1: METRONIDAZOLE: INTRA ROOTCANAL ROUTE - 100uL LIQUID FORMULATION, ONE DOSE, DAY 1.
Control Intervention1: METRONIDAZOLE: ORAL ROUTE - 400mg TABLET FORMULATION, ONE DOSE, DAY 1.
Sponsors
SAJANI RAMACHANDRAN
UR Anoop Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients reporting with pulpitis 2. Consenting adult patients above the age of 18 years 3. Patients requiring root canal treatment for maxillary 1st molar 4. Patients with dental caries with pulp exposure 5. Patients with no contra-indications for root canal procedure 6. Patients who have no known systemic problems and are not on regular medications
Exclusion criteria
Exclusion criteria: 1. Patients with periapical lesions not involving the pulp 2. Patients with known allergy to metronidazole 3. Patients who have taken metronidazole or any other drugs for the past 72 hours 4. Patients who have bleeding disorders, liver and kidney problems or are on anti-platelet drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the blood level of orally administered metronidazole with locally administered metronidazole through a drug delivery system at specified time intervals,Timepoint: 30 minutes and 90 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactSAJANI RAMACHANDRAN
PONDICHERRY INSTITUTE OF MEDICAL SCIENCE PONDICHERRY
Outcome results
None listed