Health Condition 1: N925- Other specified irregular menstruation
Conditions
Interventions
Intervention1: inj. Ketamine and Dexmedetomidine: Ketamine 1 mg/kg and Dexmedetomidine 0.5 mcg/kg combined in single syringe given IV slow over 2 min
Intervention2: inj propofol and ketamine: inj prop
Sponsors
Ananta institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients of abnormal uterine bleeding scheduled for elective endometrial sampling American Society of Anaesthesiology I and II
Exclusion criteria
Exclusion criteria: History of cardiovascular diseases e.g. ischemic heart disease, conduction defects, etc. History of compromised renal / hepatic / neuronal functions. Uncontrolled Hypertension and Diabetes History of alcohol, substance abuse, chronic use of analgesic and sedatives, psychiatric disorders •Patients on beta blocker or having persistent bradycardia with HR •Drug allergy •Procedure lasting for >30 min. •Any surgical complications during D& C e.g. uterine perforation, excessive bleeding etc. •Viable Pregnancy, acute PID, undiagnosed genital tract bleeding, mass in vagina or cervix, severe arthritis hip bone, bleeding disorders, virgin females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to onset of sedation (Ramsay sedation score RSS 6) and recovery from sedation (RSS 3)Timepoint: Time to onset of sedation (Ramsay sedation score RSS 6) and recovery from sedation (RSS 3) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Intraoperative Haemodynamics (Heart Rate, Blood Pressure, Spo2, Respiratory rate) 2.Post op recovery score ( Modified Aldrete Score) 3.Duration of analgesia Timepoint: 0min, 10, 20, 30 min | — |
Countries
India
Contacts
Public ContactAnkita Kaasat
Ananta institute of medical sciences
Outcome results
None listed