Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: 0.04% polyhexanide solution: The subcutaneous soft tissue will be irrigated with 500 ml of a 0.04% polyhexanide solution for a duration of 1 minute ( contact time).
The whole surface o
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: All elective patients above 18 years of age who are undergoing elective midline laparotomy
Exclusion criteria
Exclusion criteria: 1. Patients undergoing other than elective midline laparotomy 2. Patients who has known hypersensitivity or allergy to one of the irrigation solutions. 4. Pregnant or breast-feeding women 5. Patients with severe immunosuppression 6. Presence of concurrent abdominal wall infection 7. Preoperative systemic antibiotic therapy within 5 days prior to surgery 8. Previous abdominal surgery within the last 30 days or planned re-laparotomy within the next 30 days 9. Patients who are not giving consent 10. Surgery of the abdominal wall (hernia mesh repair) 11. Participating in another clinical trial that interferes with the primary or secondary outcomes of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of superficial Surgical site infection WITHIN 30 DAYS OF surgeryTimepoint: Incidence of superficial Surgical site infection identified as defined by centre of disease control and prevention classification within 30 days of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Post irrigation presence of microbesTimepoint: Post irrigation wound swab positivity;Post Operative painTimepoint: Measured based on numerical analogue scale on pod 30 | — |
Countries
India
Contacts
Public ContactAvinash S R
JIPMER
Outcome results
None listed