A Randomized, Clinical Study to evaluate the Efficacy and Safety of Polyherbal Unani Formulation in Acne Vulgaris.

A Randomized, Parallel Group, Open Label, Active Controlled Clinical Study to evaluate the Efficacy and Safety of a Polyherbal Unani Formulation in the Management of ButhÅ«r Labaniyya (Acne Vulgaris)

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/050164

Enrollment

Registered

2023-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Polyherbal Unani Formulation: Dosage Form: ointment Dose: As per required Mode of application: Local application once daily at bed time Duration: 6 weeks Composition: Khub kalan (Sisymb

Eligibility

Inclusion criteria

Inclusion criteria: 1. Clinically stable patients 2. Patient having chronicity 4 months to 1 year 3. Patients having the following symptoms of Buthur Labaniyya: Comedones Papules Pustules Nodules Itching Erythema

Exclusion criteria

Exclusion criteria: 1. Patients aged 35 years 2. Pregnant or Lactating Women 3. Patients on corticosteroid or anticonvulsant therapy or taking oral contraceptives 4. Patients suffering from other concomitant diseases, like acne rosacea, acne fulminans, acne necrotica, psoriasis, eczema, etc. 5. Significant Pulmonary/Cardiovascular/Hepato-renal Dysfunction 6. Patient not willing to attend treatment schedules regularly

Design outcomes

Primary

Measure	Time frame
Outcome measure will be assessed using following parameters: 1. Reduction in Global Acne Grading System 2. Reduction in Cooks Acne Grading Scale 3. Reduction in Dermatology Life Quality Index 4. Improvement in Visual Analogue Scale.Timepoint: 42 days	—

Secondary

Measure	Time frame
Systemic Safety AssessmentTimepoint: 42 days	—

Countries

India

Contacts

Public ContactDr Tahoora Tamkanat

National Research Institute of Unani Medicine for Skin Disorders

aarzu763@gmail.com9032519286

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026