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Comparing two doses of Pregabalin for prevention of fasciculations and myalgia caused by Succinylcholine

Comparison of two doses of Pregabalin for preventing Succinylcholine-induced fasciculations and myalgia in patients undergoing surgery under General Anaesthesia: A Randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/03/050162
Enrollment
201
Registered
2023-03-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Capsule PREGABALIN: A drug used for Neuropathic pain,fibromyalgia,convulsions,etc, Route:Oral Capsule, Dosage:either 75mg or 150mg, Frequency:Single dose 2 hours prior to surgery Contro

Sponsors

Shri B M Patil Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing surgery under General Anaesthesia. ASA grade 1 or 2

Exclusion criteria

Exclusion criteria: Patients with drug allergies Seizure history Cardiac diseases Impaired kidney or Liver function Raised intracranial pressure or intraocular pressure Patients on Antiepileptics,antidepressants,calcium channel blockers Pregnant and Lactating Females

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of two doses of Pregabalin in preventing Succinylcholine-Induced fasciculations and myalgiaTimepoint: 2 hours—

Secondary

MeasureTime frame
To compare the hemodynamic stability and 24 hour post operative analgesic requirement of the patients who received Pregabalin and the patients who received only PlaceboTimepoint: 24 hours—

Countries

India

Contacts

Public ContactMalavika Sasidharan

Shri B M Patil Medical College, Vijayapura

renuka312@gmail.com9886492178

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026