Assessing change in the smell and taste after surgery when patient use gargle with local anesthesia drug 2% lignocaine hydrochloride and nebulized with 4% lignocaine before the surgery during the neck spine surgery where tracheal tube will be placed by fiberoptic scope for anesthesia.

Evaluation of the postoperative olfactory and gustatory dysfunction following gargle with 2% lignocaine hydrochloride oral topical solution and nebulization with 4% lignocaine in the patients undergoing fiberoptic intubation for cervical spine surgery under general anaesthesia: a prospective, randomised, double blind controlled trial.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

CTRI

Registry ID

CTRI/2023/02/050161

Enrollment

100

Registered

2023-02-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex with American Society Anaesthesiologists’ physical status I- II, age between 18 and 70 years, scheduled for fiberoptic intubation for cervical spine surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients with recent airway infection, allergic rhinitis, nasal polyps, history of alcoholism, smoking, anticipated very difficult intubation, mental retardation, psychiatric illness, cognitive impairment, neurosurgical or oto-rhino-laryngeal surgery and, patients with the previous history of COVID infection with olfactory/ and gustatory deficits

Design outcomes

Primary

Measure	Time frame
postoperative olfactory (using Indian Smell Identification Test) and gustatory dysfunction (to test five basic tastes ie, sweet, salty, sour, bitter, and umami or savory)Timepoint: The first test will be done the night before the surgery or on the morning before the scheduled surgery.Subsequent test will be done 3 h after the end of anaesthesia (time point T1) and postoperative day 2 i,e 24 hours after surgery (time point T2), day 3 (time point T3) and day 7 or at discharge, whichever will be earlier (time point T4). Patient will be contacted telephonically at 3 months after the surgery during follow-up for any complain of smell or taste dysfunction.	—

Measure

Time frame

postoperative olfactory (using Indian Smell Identification Test) and gustatory dysfunction (to test five basic tastes ie, sweet, salty, sour, bitter, and umami or savory)Timepoint: The first test will be done the night before the surgery or on the morning before the scheduled surgery.Subsequent test will be done 3 h after the end of anaesthesia (time point T1) and postoperative day 2 i,e 24 hours after surgery (time point T2), day 3 (time point T3) and day 7 or at discharge, whichever will be earlier (time point T4). Patient will be contacted telephonically at 3 months after the surgery during follow-up for any complain of smell or taste dysfunction.

—

Secondary

Measure	Time frame
1. Determine the relationship of the following variables with postoperative olfactory and gustatory dysfunction: age, sex, concomitant medication. 2. Long term effect of anesthesia on olfactory and gustatory dysfunction Timepoint: 3 months follow up	—

Countries

India

Contacts

Public ContactDR DEVENDRA GUPTA

SGPGIMS, Lucknow

drdevendragpt@yahoo.com9199197548

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026

Assessing change in the smell and taste after surgery when patient use gargle with local anesthesia drug 2% lignocaine hydrochloride and nebulized with 4% lignocaine before the surgery during the neck spine surgery where tracheal tube will be placed by fiberoptic scope for anesthesia.

Conditions

Related papers

Interventions

Sponsors

Eligibility

Inclusion criteria

Exclusion criteria

Design outcomes

Primary

Secondary

Countries

Contacts

Outcome results