Health Condition 1: O992- Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium Health Condition 2: O099- Supervision of high risk pregnancy, unspecified
Conditions
Interventions
None listed
Sponsors
Intramural Grant of SGPGIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1.Singleton pregnancy 2.Spontaneous conception 3.10-13 weeks 6 days of gestation 4.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Previous bariatric surgery 2.Known pre-existing diabetes mellitus or under treatment with metformin; 3.Known case of Hypertension, thyroid disease, kidney disease, hepatic, cardiovascular and cerebrovascular disease before pregnancy 4.Use of medications that might affect Glucolipid metabolism 5.No acute infection in last 2 weeks 6.No antibiotics used in during pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify serum metabolomic markers associated with gestational diabetes mellitus (GDM) and to examine the differences of these markers between pregnant women with Gestational Diabetes Mellitus and without Gestational Diabetes Mellitus in the First trimester of pregnancy. Timepoint: 7 to 13 weeks and 6 days during First trimester of pregnancy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To evaluate correlation of significant metabolites with various Demographical and Biochemical parameters. Timepoint: First trimester of pregnancy;2.To evaluate the potential clinical utility of serum biomarkers serum adiponectin and serum Irisin for first-trimester prediction of GDMTimepoint: first trimester of pregnancy | — |
Countries
India
Contacts
Public ContactProf Indu Lata
SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES
Outcome results
None listed